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Mass Spectrometry (MS) is a major technique in most of the proteomics platforms. All mass spectrometry techniques require high quality calibration mixtures with respect to their ionization mode, ionization technique and type of analyzers irrespective of the mass spectrometer used. In most of the cases, for both positive and negative mode ionizations the researchers require different calibration mixture to acquire better ionization, tuning, high accurate mass and sensitivity. The soft ionization techniques such as ESI (Electrospray Ionization) and MALDI (Matrix Assisted Laser Desorption Ionization) require calibration mixtures. Also, different calibration mixtures are required for variety of MS analyzers such as triple quadrupole (QQQ), ion trap/orbitrap and TOF (time of flight). Similarly, another major product required in mass spectrometry analysis is MALDI matrices. Alfa Aesar offers calibration mixture, protein, peptide mass spectrometry standards and MALDI matrices.